Phenibut is a derivative of the neurotransmitter GABA. The addition of the phenyl ring gives it the ability to cross the blood-brain barrier.
Discovered in the Soviet Union in the 1960s Phenibut has been said to have nootropic actions, for its ability to improve neurological functions. Phenibut is generally accepted to also have anxiolytic functions in both animals and humans. It is used in Russia as a neuropsychotropic drug, and in the Soviet Union has been used to treat a wide range of ailments including PTSD, anxiety, and insomnia.
Common doses range from 250mg-1500mg twice daily, or as needed.
Khaunina, R.A. (1964). "Tranquilizing effects of beta-phenyl-gamma-aminobutyric acid". Byulleten Experimentalnoi Biologii i Meditsiny 57 (1): 54–58.
Lapin, Izyaslav (December 2001). "Phenibut (β-Phenyl-GABA): A Tranquilizer and Nootropic Drug". CNS Drug Reviews 7 (4): 471–481.
Shulgina GI (1986). "On neurotransmitter mechanisms of reinforcement and internal inhibition". Pavlov J Biol Sci 21 (4): 129–40.
Serving Size 1 Capsule
Servings Per Container 120
Amount Per Serving % Daily Value
Phenibut (B-phenyl-y-Aminobutyric Acid) 500 mg *
* Percent Daily Values are based on a 2,000 calorie diet
As a dietary supplement, take 1 to 2 capsules 1 to 3 times per day, but do not exceed 4 total capsules in a 24 hour period.
Not for use by individuals under the age of 18 years. Do not use if pregnant or nursing. Consult a Physician before using this or any product if you have, or have a family history of, including but not limited to high blood pressure, cardiac arrhythmias, heart, liver, kidney, thyroid, or psychiatric disease, phenochromacytoma, diabetes, asthma, recurrent head aches, anemia, nervousness, anxiety, depression or other psychiatric condition, peptic ulcers. Parkinson's disease, glaucoma, difficulty in urinating, prostate enlargement, or seizure disorder, or if you are using a monoamine Oxidase inhibitor (MAOI) or any other dietary supplement, prescription drug, or over-the-counter-drug containing ephedrine, pseudoephedrine, or phenylpropanolamine (ingredients found in certain allergy, asthma, cough or cold, and weight control products). Do not exceed recommended serving. Exceeding recommended serving may cause serious adverse health effects, including heart attack and stroke. Discontinue use and call a physician or licensed qualified health care professional immediately if you experience rapid heartbeat, dizziness, severe headache, shortness of breath, or other similar symptoms. Keep out of reach of children.