Best CoQ10 contains pure, fermented, USP grade coenzyme Q10. CoQ10 is
a nutrient that supports heart function and promotes energy production
in cells. CoQ10 is a versatile antioxidant, which stabilizes cell
membranes, protecting them from free radical damage. CoQ10 can also
powerfully support immune function.*
Highlights:
-Science-based nutrition
-Dietary supplement
-Pharmaceutical grade CoQ10
-Supports heart function*
-Enhances energy production in cells*
-Antioxidant protection
Benefits:
Coenzyme Q10 is a vitamin-like nutrient central to energy production
at the cellular level, essential for generating metabolic energy in
the form of ATP. CoQ10 is also a versatile antioxidant, stabilizing
cell membranes (helping to protect them from free radical damage) and
contributing to their fluidity. Coenzyme Q10 levels decrease with age,
a factor that may actually contribute to the aging process. Since food
content of CoQ10 can be very low, many healthcare providers recommend
supplementing with Coenzyme Q10.
Due to the extraordinary energy requirements of our hardworking heart,
the highest concentration of CoQ10 is found in heart muscle tissue.
Coenzyme Q10 is known to support the heart through mitochondrial
bioenergetics, the process of cellular energy transformation. On top
of this, CoQ10 helps to promote overall cardiovascular health by
confronting oxidative stress in heart and endothelial (blood vessel
wall) cells.
In terms of bioenergetics, CoQ10 supplementation acts to preserve
energy turnover in mitochondria—our cellular powerhouses—by keeping
ATP synthesis at optimal levels. Maintenance of normal energy
utilization and supply is crucial for maintaining the cell’s ideal
biochemical state. Based on results from clinical studies, researchers
have concluded that some segments of the population can achieve an
increase in needed ATP production in addition to other benefits from
CoQ10 supplementation.
Also in the cardiovascular realm, there has been longstanding interest
in the use of Coenzyme Q10 supplementation to work against the
oxidative stress that takes a toll on circulating blood lipids. In
addition to reacting directly with peroxyl radicals, CoQ10 indirectly
helps quench radicals by regenerating the active form of vitamin E.
This type of antioxidant activity is key to enhancing the structural
integrity of lipids and supporting healthy blood vessels and
circulation.
Given all of these cardiovascular findings, it may not be surprising
to learn that the effect of CoQ10 on blood pressure has been a topic
of scientific research since 1975. A metaanalysis of such studies
noted Coenzyme Q10 supplementation as one useful and safe tool in the
maintenance of a healthy blood pressure, complementing the endothelial
support and antioxidant advantages it provides.
Helps Replenish Losses From Statins*
Many widely used statin drugs that are taken to alter cholesterol
levels also have an unfortunate nutritional side effect: they are
known to deplete the body’s CoQ10 by blocking its synthesis.
Supplemental CoQ10 can be taken in anticipation of this particular
drawback, with 30 days of CoQ10 supplementation in a recent study
showing positive change in undesirable effects attributed to
statininduced CoQ10 disruption.
Supports Immune Function*
When the immune system goes into battle for us, immune cells need
large amounts of energy to carry out their defensive functions. Among
the most metabolically active of the body’s cells, they accordingly
have large requirements for CoQ10. Although not extensively studied in
humans, there is some clinical evidence that supplementing with CoQ10
can benefit the immune response. Researchers suggest that these immune
enhancing actions can particularly benefit elderly people, since CoQ10
production decreases with age (levels steadily fall after the age of
40).
Versatile Antioxidant Support* Regenerates Other Antioxidants in the Body*
Within the cell, antioxidants work as a team to keep free radicals
from damaging cell structures. In order to neutralize a free radical,
an antioxidant such as vitamin E must give up an electron, which means
it becomes oxidized. Before it can function as an antioxidant once
again, it must be regenerated back to its "reduced" form by gaining an
electron to replace the donated electron. For this, it needs the help
of other antioxidants. Vitamin C, vitamin E, glutathione, and
alpha-lipoic acid are key antioxidants that cycle between their
oxidized and reduced forms. This is necessary to maintain the balance
between oxidation and its reverse––the neutralization of free radicals
by antioxidants.
Coenzyme Q10 is a unique fat-soluble antioxidant referred to as
ubiquinone —or ubiquinol in its reduced form—because it is
“ubiquitous” (everywhere present), that is found in almost all living
cells. In a randomized, double-blind, placebo-controlled study where
subjects had lower than usual blood concentrations of the antioxidant
vitamins A, C, E, and beta-carotene, 28 days of CoQ10 supplementation
provided a significant increase in blood levels of these antioxidants,
compared to placebo. Vitamin E regeneration upon administration of
CoQ10 has been observed in several studies.
The Research Keeps Moving Forward*
Beyond its essential bioenergetic actions and the fat-soluble
antioxidant power it offers in helping to secure the integrity of our
neurons and cardiovascular tissue, Coenzyme Q10 is being studied for
several different health applications. Researchers have concluded that
due to its ability to inhibit collagenase, CoQ10 can aid in the
reconditioning of wrinkled skin (caused by ultraviolet-B light).
Numerous studies have been carried out to investigate the relationship
between CoQ10 and exercise, physical performance, or energy
metabolism. In one such recent study, researchers looked at the effect
of CoQ10 supplementation on the autonomic nervous system, which is
integral to energy metabolism. They discovered that subjects
administered supplemental CoQ10 experienced increased oxidation of fat
(enhanced fat metabolism) during low intensity exercise. Although
larger studies are needed to confirm this finding, it introduces
exciting new prospects for the use of supplemental CoQ10.
Supplement Facts:
Serving Size: 1 softgel
Servings Per Container: 60
Amount Per Serving % Daily Value *
Coenzyme Q10 100mg *
* Percent Daily Values are based on a 2,000 calorie diet.
* Percent Daily Value not established.
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