Max Body Supplements: Strontium Bone Maker 340mg 120VCaps

Strontium is a naturally occurring mineral present in water and food. Trace amounts of strontium are found in the human skeleton. Strontium has an affinity for bone and is taken up at the bone matrix crystal surface. The influence of strontium on the bone metabolism has been researched since the 1950's. Studies indicate that strontium positively affects bone metabolism to promote bone formation and decrease bone resorption, leading to normalized bone density.

The Role of Stable Strontium in Human Bone

Strontium is found naturally in the human skeleton. The level of strontium in bone tissue is approximately 3.5% of the calcium content of bone. Strontium taken orally through the diet and from supplements is preferentially incorporated into the teeth and bones. Research suggests that the oral absorption of strontium is dependent on age and decreases with increasing age. Scientists have suggested two methods of absorption of strontium from the gastrointestinal tract: passive diffusion and carrier-mediated absorption. In adults, strontium is absorbed to a lesser extent than calcium, possibly due to the larger molecular size of strontium in comparison to the calcium molecule. Both calcium and strontium compete with one another for absorption in the intestines. High dietary intake of calcium has been shown to reduce concurrent absorption of strontium. It has been proposed that when both elements are present together, twice the amount of calcium is absorbed from the intestines in comparison with strontium.

Animal studies suggest that extremely high dietary intakes of strontium, in the absence of adequate calcium intake, can actually disturb bone mineralization. At such concentration levels strontium replaces calcium ions in bone. The unbalanced incorporation of strontium into bone tissue in the place of calcium may cause a disturbance of the bone lattice, resulting in decreased bone mineral density. It is precisely for this reason that calcium intake must be adequate when supplementing with strontium.

Further studies in animals reveal that strontium given as a part of the normal diet (when calcium intake is adequate) may have profound effects on bone formation and density. Oral administration of strontium doses to rats was shown to enhance the rate of bone formation and trabecular bone density.

Highlights:

-Science-based nutrition
-Dietary supplement
-Helps maintain strong, healthy bones.*

Benefits:

Helps Maintain Strong, Healthy Bones* Mechanism of Action

Strontium is a bone-seeking mineral incorporated by ionic substitution for calcium onto the crystal surface of bone. Researchers have looked at the therapeutic potential of strontium based on in vitro, animal and human studies. After assessing and analyzing the results of several investigations, scientists theorize that strontium may benefit bone health via a two-pronged effect. It appears that strontium interacts with the cells responsible for the normal bone remodeling process. The cells responsible for bone formation are known as osteoblasts, and the cells responsible for bone breakdown, or resorption, are called the osteoclasts. Strontium may stimulate the replication of pre-osteoblasts, leading to an increased proliferation of osteoblasts (cells that build bone). This causes an increased synthesis of bone matrix. In terms of effects on osteoclasts (cells responsible for bone resorption), in vitro work shows that strontium directly inhibits their activity and prevents bone breakdown.

Animal Studies

Animal studies have shown that supplementation with strontium is extremely beneficial as a bone building catalyst.

In one such study, strontium administered at low doses has been shown to increase the number of bone forming sites in thighbones of adult rats, without adverse effects on the mineral content of bone or mineralization of the organic bone matrix. A second study in rats indicated that strontium could reverse bone loss associated with a deficiency of the hormone estrogen in females.

Clinical Trials

Multiple clinical studies utilizing different forms of strontium have been conducted since the 1950s. Stable strontium as gluconate, carbonate, lactate and chloride have all been used in various trials that have reported efficacy of supplemental strontium in promoting healthy bones. Regardless of the form, it is the elemental strontium itself that exerts the positive effect on bone. While all of the various forms have a bioavailability of between 25 and 30%, gastric tolerance is reportedly better with strontium citrate9, the form used in Strontium Bone Maker.

Supplement Facts:

Serving Size: 2 capsules
Servings Per Container: 60
Amount Per Serving % Daily Value *
Strontium 680 mg *
(elemental) (from 1944mg Strontium citrate)

* Percent Daily Value not established.

Other Ingredients:
Modified cellulose (vegetarian capsule), cellulose, magnesium stearate (vegetable source).

Directions:
Take two capsules daily with or without food. For maximum absorption and benefit, do not take at the same time as calcium or milk products. Be sure to take at least the RDA of calcium and Vitamin D3

The best way to take your strontium is in the morning on an empty stomach as you will digest it quickly and you can then after one hour have your breakfast and take all your vitamins. Take the two caps at the same time. If you cannot swallow capsules please open capsule and put into apple sauce but not into any dairy products as the calcium in it will compete with the Strontium Bone Maker's absorption.

Warnings:
KEEP OUT OF REACH OF CHILDREN. Supplementing with strontium is an effective means for supporting bone health and optimal bone density. When taken orally as recommended, strontium is well- tolerated and very safe. It is important to ensure calcium and vitamin D intakes are adequate when supplementing with strontium. This is underscored by earlier research on animals suggesting that increasing the intake of strontium via diet may demineralize bone when calcium is deficient. In rats with chronic kidney failure, strontium has been shown to cause osteomalacia, a condition in which bone is softened due to lack of mineral content. For this reason, people on kidney dialysis should not use strontium supplements. There are no published reports of toxic effects in humans due to strontium overdosing.

Caution:
To prevent mouth or throat irritation do not open capsule and pour contents directly into mouth

Note:
Individuals with a severe renal impairment should check with a healthcare practitioner before using this product

Does Not Contain:
Milk, egg, wheat, gluten, corn, soy, sugar, sweeteners, starch, salt, or preservatives

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Strontium is a naturally occurring mineral present in water and food. Trace amounts of strontium

are found in the human skeleton. Strontium has an affinity for bone and is taken up at the bone

matrix crystal surface. The influence of strontium on the bone metabolism has been researched

since the 1950's. Studies indicate that strontium positively affects bone metabolism to promote

bone formation and decrease bone resorption, leading to normalized bone density. 
 
The Role of Stable Strontium in Human Bone 
 
Strontium is found naturally in the human skeleton. The level of strontium in bone tissue is

approximately 3.5% of the calcium content of bone. Strontium taken orally through the diet and

from supplements is preferentially incorporated into the teeth and bones. Research suggests that

the oral absorption of strontium is dependent on age and decreases with increasing age.

Scientists have suggested two methods of absorption of strontium from the gastrointestinal

tract: passive diffusion and carrier-mediated absorption. In adults, strontium is absorbed to a

lesser extent than calcium, possibly due to the larger molecular size of strontium in comparison

to the calcium molecule. Both calcium and strontium compete with one another for absorption in

the intestines. High dietary intake of calcium has been shown to reduce concurrent absorption of

strontium. It has been proposed that when both elements are present together, twice the amount

of calcium is absorbed from the intestines in comparison with strontium. 
 
Animal studies suggest that extremely high dietary intakes of strontium, in the absence of

adequate calcium intake, can actually disturb bone mineralization. At such concentration levels

strontium replaces calcium ions in bone. The unbalanced incorporation of strontium into bone

tissue in the place of calcium may cause a disturbance of the bone lattice, resulting in

decreased bone mineral density. It is precisely for this reason that calcium intake must be

adequate when supplementing with strontium. 
 
Further studies in animals reveal that strontium given as a part of the normal diet (when

calcium intake is adequate) may have profound effects on bone formation and density. Oral

administration of strontium doses to rats was shown to enhance the rate of bone formation and

trabecular bone density. 
 
Highlights: 
 
-Science-based nutrition 
-Dietary supplement 
-Helps maintain strong, healthy bones.* 
 
Benefits: 
 
Helps Maintain Strong, Healthy Bones* Mechanism of Action 
 
Strontium is a bone-seeking mineral incorporated by ionic substitution for calcium onto the

crystal surface of bone. Researchers have looked at the therapeutic potential of strontium based

on in vitro, animal and human studies. After assessing and analyzing the results of several

investigations, scientists theorize that strontium may benefit bone health via a two-pronged

effect. It appears that strontium interacts with the cells responsible for the normal bone

remodeling process. The cells responsible for bone formation are known as osteoblasts, and the

cells responsible for bone breakdown, or resorption, are called the osteoclasts. Strontium may

stimulate the replication of pre-osteoblasts, leading to an increased proliferation of

osteoblasts (cells that build bone). This causes an increased synthesis of bone matrix. In terms

of effects on osteoclasts (cells responsible for bone resorption), in vitro work shows that

strontium directly inhibits their activity and prevents bone breakdown. 
 
Animal Studies 
 
Animal studies have shown that supplementation with strontium is extremely beneficial as a bone

building catalyst. 
 
In one such study, strontium administered at low doses has been shown to increase the number of

bone forming sites in thighbones of adult rats, without adverse effects on the mineral content

of bone or mineralization of the organic bone matrix. A second study in rats indicated that

strontium could reverse bone loss associated with a deficiency of the hormone estrogen in

females. 
 
Clinical Trials 
 
Multiple clinical studies utilizing different forms of strontium have been conducted since the

1950s. Stable strontium as gluconate, carbonate, lactate and chloride have all been used in

various trials that have reported efficacy of supplemental strontium in promoting healthy bones.

Regardless of the form, it is the elemental strontium itself that exerts the positive effect on

bone. While all of the various forms have a bioavailability of between 25 and 30%, gastric

tolerance is reportedly better with strontium citrate9, the form used in Strontium Bone

Maker. 
 
Supplement Facts: 
 
Serving Size: 2 capsules 
Servings Per Container: 60 
Amount Per Serving % Daily Value * 
Strontium 680 mg * 
(elemental) (from 1944mg Strontium citrate) 
 
* Percent Daily Value not established. 
 
Other Ingredients: 
Modified cellulose (vegetarian capsule), cellulose, magnesium stearate (vegetable source). 
 
Directions: 
Take two capsules daily with or without food. For maximum absorption and benefit, do not take at

the same time as calcium or milk products. Be sure to take at least the RDA of calcium and

Vitamin D3 
 
The best way to take your strontium is in the morning on an empty stomach as you will digest it

quickly and you can then after one hour have your breakfast and take all your vitamins. Take the

two caps at the same time. If you cannot swallow capsules please open capsule and put into apple

sauce but not into any dairy products as the calcium in it will compete with the Strontium Bone

Maker's absorption. 
 
Warnings: 
KEEP OUT OF REACH OF CHILDREN. Supplementing with strontium is an effective means for supporting

bone health and optimal bone density. When taken orally as recommended, strontium is well-

tolerated and very safe. It is important to ensure calcium and vitamin D intakes are adequate

when supplementing with strontium. This is underscored by earlier research on animals suggesting

that increasing the intake of strontium via diet may demineralize bone when calcium is

deficient. In rats with chronic kidney failure, strontium has been shown to cause osteomalacia,

a condition in which bone is softened due to lack of mineral content. For this reason, people on

kidney dialysis should not use strontium supplements. There are no published reports of toxic

effects in humans due to strontium overdosing. 
 
Caution: 
To prevent mouth or throat irritation do not open capsule and pour contents directly into

mouth 
 
Note: 
Individuals with a severe renal impairment should check with a healthcare practitioner before

using this product 
 
Does Not Contain: 
Milk, egg, wheat, gluten, corn, soy, sugar, sweeteners, starch, salt, or preservatives