PRIMAFORCE AGMATINE SULPHATE POWDER
Agmatine is a metabolic byproduct of Arginine produced through a process called decarboxylation. Agmatine is basically Arginine with the carboxylic acid end removed. Agmatine produces the byproducts Guanidino-butyladehyde and the polyamines putruscene, spermine, and spermidine which are involved in cell growth. Agmatine is found in tissues throughout the body and is synthesized and stored in astrocytes, glial cells in the brain and spinal cord, which provide structural and metabolic support to the nervous system among other actions. Agmatine acts as a neurotransmitter and neuromodulator with a vast array of actions in the body.
Agmatine stimulates the release of insulin and uptake of calcium in pancreatic cells leading to improved insulin sensitivity.
What does Agmatine do?
*Binds to Imidazoline Receptors providing analgesia and assisting in pain management.
*Binds to Alpha2-Adrenergic and Imidazoline Receptors of endothelial cells increasing Nitric Oxide (NO) production thereby decreasing blood pressure.
*Inhibits monoamine oxidase (MAO) leading to antidepressant effects. Antagonist of the N-Methyl-D-Aspartate (NMDA) receptor providing a potential neuroprotective role.
*Simulates the release of catecholeamines (norepinephrine, epinephrine, and dopamine) assisting in stress management.
*Increases release of GnRH from the hypothalamus, stimulating secretion of LH/FSH which could increase testosterone production in the testes.
*Inhibits Nitric Oxide Synthase (NOS), specifically iNOS and nNOS, leading to increased potential muscle pumps.
*Improve kidney function through stimulation of the Glomerular Filtration Rate (GFR) Agmatine provides many health benefits, but of interest to fitness enthusiasts it provides: Improved insulin sensitivity (which can assist in improving body composition)
*Potential to increase testosterone production
*Assists in stress reduction Increase in muscle pumps
Serving Size: 750 mg
Servings Per Container 30
Amount Per Serving % Daily Value
Agmatine Sulfate 750 mg +
*percent Daily Values are based on a 2,000 calorie diet.
Dosages of 1.5- 3.5 grams per day of Agmatine Sulfate have been shown to be safe in humans, though 3.5 grams caused mild diarrhea and nausea. The generally agreed upon dosing recommendation for Agmatine for physique-related benefits is 1,000 mg first thing in the morning on an empty stomach.
You should not take Agmatine Sulfate if you have any prior medical condition, and should always consult your health practitioner before beginning any exercise or supplementation program. Agmatine Sulfate is not suitable as a sole source of nutrition and should be used in conjunction with an appropriate physical training or exercise program. Not suitable for children under the age of 18 years or pregnant women. The statements on this label have not been evaluated by the Food and Drug Administration. Agmatine Sulfate is not intended to diagnose, treat, cure, or prevent any disease.